Publication & Award

CLSTN3β enforces adipocyte multilocularity to facilitate lipid utilization

Kevin Qian Research Award
As an MD PhD graduate student at UCLA, Kevin published a landmark paper in the journal Nature describing the way in which fat cells (adipocytes) store lipids in droplets and ultimately burn these lipids in ways that can promote weight loss. Our DoM Education Team honored Kevin Quian, MD, PhD with the William N. Valentine Award for Excellence in Internal Medicine. Dr. Valentine was the second chair of medicine from 1963-1971. Dr. Valentine was internationally acclaimed for his seminal research that describes the fundamentals of red blood cell physiology, particularly his work in describing the role of changes in metabolic enzyme function that could contribute to disorders such as hemolytic anemia. Dr. Qian is a member of our physician scientist training residency program, now integrally linked with the STAR Program. The award recognizes his superior performance as a scholar in Internal Medicine and outstanding scholarly achievements throughout medical school.

Qian, K., Tol, M.J., Wu, J. et al. CLSTN3β enforces adipocyte multilocularity to facilitate lipid utilization. Nature 613, 160–168 (2023).

Kevin Qian

Kevin Qian, MD, PhD

Resident

Kevin Qian, MD, PhD
(PGY-1)

Subspecialty

Endocrinology

Type of Research

Publication

Journal

Nature

Publication

Risk of severe immune-related adverse events in cancer patients with pre-existing autoimmunity receiving immune checkpoint inhibitor therapy

Dr. Isaacs et al "study suggests that patients with pre-existing autoimmune disease can be treated with ICI cancer therapies and experience rates of severe irAEs and overall survival that are similar to those of the general population. These data can aid oncologists in discussing risks and benefits of ICIs when treating patients with pre-existing autoimmunity and solid tumors."

Isaacs DJ, Kathuria-Prakash N, Hilder R,etal.  Risk of severe immune-related adverse events incancer patients with pre-existing autoimmunity receiv-ing immune checkpoint inhibitor therapy.Curr CancerRep,2024,5(1): 168-180.

Dayna Isaacs

Dayna Isaacs, MD

Resident

Dayna Isaacs, MD
(PGY-3)

Subspecialty

Hematology/Oncology

Type of Research

Publication

Journal

Current Cancer Reports

Presentation, Award, & Publication

Racial and Ethnic Disparities in Colorectal Cancer Screening and Outcomes

Megan received the 2022 AGA Abstract Award for Health Disparities Research for her oral presentation “Decline In Colorectal Cancer Screening Rates in Federally Qualified Health Centers in the United States between 2019 and 2020."

Megan Abstract Award
McLeod MR, Galoosian A, May FP. Racial and Ethnic Disparities in Colorectal Cancer Screening and Outcomes. Hematol Oncol Clin North Am. 2022;36(3):415-428.
Megan McLeod, MD

Megan McLeod, MD, MSCR

Resident

Megan McLeod, MD
(PGY-2*)

*Now GI Fellow (PGY-4) at UCLA

Subspeciality

Gastroenterology

Type of research

Publication

Journal

Hematology/Oncology Clinics of North America

Op-Med

We Should Disaffiliate from the AOA Honor Medical Society

Isaacs_Op_Ed

"Institutional affiliation with the AOA perpetuates a flawed system that disproportionately benefits privileged trainees while excluding those that do not fit the socially dominant mold. This is diametrically opposed to justice, equity, and medicine’s oath to “Do No Harm.” Terminating an institution’s local chapter, or “disaffiliating” from the national AOA organization, sends a compelling message. Medical education needs alternative, equitable mechanisms to recognize the excellence of trainees, and graduate medical training programs must adopt holistic review processes that consider the structural and contextual factors shaping applicants’ accomplishments. Moreover, disaffiliation is an effective means by which physicians and trainees alike can serve as national leaders on this issue as well as inspire other institutions to follow. We urge medical students, residents, fellows, and faculty to collaborate in disaffiliating their institutions from the AOA as one tangible, antiracist step to advancing equity in medicine."

Mabeza RM & Isaacs D. We Should Disaffiliate from the AOA Honor Medical Society. https://opmed.doximity.com/articles/we-should-disaffiliate-from-the-aoa-honor-medical-society. Accessed 6 Feb 2024. 
Dayna Isaacs

Dayna Isaacs, MD

Resident

Dayna Isaacs, MD
(PGY-3)

Type of research

Opinion Medicine

Website

Doximity Op-Med

Book Chapter

Pulmonary Alveolar Proteinosis

Encyclopedia Resp Medicine

A book chapter detailing the current state of knowledge regarding pulmonary alveolar proteinosis, including its clinical presentation, epidemiology, diagnosis, pathophysiology, and treatment. The chapter also includes new advances in the field, as well as clinical trials that are ongoing. The purpose of the chapter is to educate other pulmonary clinicians and researchers within the field in order to guide diagnosis, management, and treatment of pulmonary alveolar proteinosis, as well as to provide information for scientists who are interested in studying this rare lung disease.

Wang S, Dai DW, Lee E, Wang TS. Pulmonary Alveolar Proteinosis. Encyclopedia of Respiratory Medicine, Academic Press. 2022; Second Edition: 466-474.

Stephanie Wang

Stephanie Wang, MD

Resident

Stephanie Wang, MD
(PGY-2*)

*Now Pulm/Crit Fellow (PGY-4) at Brigham and Women's Hospital

Subspecialty

Pulmonary/Critical Care

Type of research

Book Chapter

Book title

Encyclopedia of Respiratory Medicine