Yucheng Yao

Title(s)Professor-in-Residence, Medicine
SchoolMedicine
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    Switch of Osteogenesis in Vascular Calcification
    NIH R01HL139675Jul 1, 2018 - Jun 30, 2022
    Role: Principal Investigator
    BMP and Notch crosstalk in cerebral arteriovenous malformations
    NIH R01NS079353Jun 1, 2012 - May 31, 2022
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. CDK1 inhibition reduces osteogenesis in endothelial cells in vascular calcification. JCI Insight. 2024 Mar 08; 9(5). Zhao Y, Yang Y, Wu X, Zhang L, Cai X, Ji J, Chen S, Vera A, Boström KI, Yao Y. PMID: 38456502.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    2. Two-step regulation by matrix Gla protein in brown adipose cell differentiation. Mol Metab. 2024 Feb; 80:101870. Zhang L, Cai X, Ma F, Qiao X, Ji J, Ma JA, Vergnes L, Zhao Y, Yao Y, Wu X, Boström KI. PMID: 38184275; PMCID: PMC10832489.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    3. Aurora Kinase A Regulates Cell Transitions in Glucocorticoid-Induced Bone Loss. Cells. 2023 10 11; 12(20). Qiao X, Yang Y, Zhao Y, Wu X, Zhang L, Cai X, Ji J, Boström KI, Yao Y. PMID: 37887278; PMCID: PMC10605378.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    4. Reply: Transitioning endothelial cells contribute to pulmonary fibrosis. Eur Respir J. 2023 09; 62(3). Wu X, Boström KI, Yao Y. PMID: 37770088; PMCID: PMC10533945.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    5. GSK3β Inhibition Ameliorates Atherosclerotic Calcification. Int J Mol Sci. 2023 Jul 19; 24(14). Cai X, Zhao Y, Yang Y, Wu X, Zhang L, Ma JA, Ji J, Boström KI, Yao Y. PMID: 37511396; PMCID: PMC10380320.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    6. COVID-19 Infection May Drive EC-like Myofibroblasts towards Myofibroblasts to Contribute to Pulmonary Fibrosis. Int J Mol Sci. 2023 Jul 15; 24(14). Wu X, Zhang D, Boström KI, Yao Y. PMID: 37511258; PMCID: PMC10380846.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    7. Cell Transitions Contribute to Glucocorticoid-Induced Bone Loss. Cells. 2023 07 08; 12(14). Qiao X, Wu X, Zhao Y, Yang Y, Zhang L, Cai X, Ma JA, Ji J, Lyons K, Boström KI, Yao Y. PMID: 37508475; PMCID: PMC10377921.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    8. Regulating the cell shift of endothelial cell-like myofibroblasts in pulmonary fibrosis. Eur Respir J. 2023 06; 61(6). Wu X, Zhang D, Qiao X, Zhang L, Cai X, Ji J, Ma JA, Zhao Y, Belperio JA, Boström KI, Yao Y. PMID: 36758986; PMCID: PMC10249020.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    9. GSK3β Inhibition Reduced Vascular Calcification in Ins2Akita/+ Mice. Int J Mol Sci. 2023 Mar 22; 24(6). Boström KI, Qiao X, Zhao Y, Wu X, Zhang L, Ma JA, Ji J, Cai X, Yao Y. PMID: 36983045; PMCID: PMC10054481.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    10. Single-Cell RNA-Seq Identifies Dynamic Cardiac Transition Program from ADCs Induced by Leukemia Inhibitory Factor. Stem Cells. 2022 10 21; 40(10):932-948. Yao J, Ma F, Zhang L, Zhu C, Jumabay M, Yao Z, Wang L, Cai X, Zhang D, Qiao X, Shivkumar K, Pellegrini M, Yao Y, Wu X, Boström KI. PMID: 35896368; PMCID: PMC9585902.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    11. The Mechanobiology of Endothelial-to-Mesenchymal Transition in Cardiovascular Disease. Front Physiol. 2021; 12:734215. Islam S, Boström KI, Di Carlo D, Simmons CA, Tintut Y, Yao Y, Hsu JJ. PMID: 34566697; PMCID: PMC8458763.
      View in: PubMed   Mentions: 16  
    12. Shifting osteogenesis in vascular calcification. JCI Insight. 2021 05 24; 6(10). Yao J, Wu X, Qiao X, Zhang D, Zhang L, Ma JA, Cai X, Boström KI, Yao Y. PMID: 33848269; PMCID: PMC8262274.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    13. Contributions of the Endothelium to Vascular Calcification. Front Cell Dev Biol. 2021; 9:620882. Zhang L, Yao J, Yao Y, Boström KI. PMID: 34079793; PMCID: PMC8165270.
      View in: PubMed   Mentions: 9  
    14. Pronethalol Reduces Sox2 (SRY [Sex-Determining Region Y]-Box 2) to Ameliorate Vascular Calcification. Arterioscler Thromb Vasc Biol. 2021 02; 41(2):931-933. Zhang D, Qiao X, Yao J, Zhang L, Wu X, Ma J, Cai X, Bostrom KI, Yao Y. PMID: 33297753; PMCID: PMC8105260.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    15. Shaping Waves of Bone Morphogenetic Protein Inhibition During Vascular Growth. Circ Res. 2020 10 23; 127(10):1288-1305. Guihard PJ, Guo Y, Wu X, Zhang L, Yao J, Jumabay M, Yao Y, Garfinkel A, Boström KI. PMID: 32854559; PMCID: PMC7987130.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    16. Pronethalol decreases RBPJκ to reduce Sox2 in cerebral arteriovenous malformation. Vasc Med. 2020 12; 25(6):569-571. Qiao X, Zhang D, Zhang L, Yao J, Wu X, Cai X, Boström KI, Yao Y. PMID: 32833597; PMCID: PMC8034816.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    17. Options for COVID-19 Entry into Pulmonary Cells. Biomed J Sci Tech Res. 2020 Aug; 29(2):22337-22338. Boström KI, Yao Y. PMID: 33283173; PMCID: PMC7717074.
      View in: PubMed   Mentions:
    18. Homeobox D3, A Novel Link Between Bone Morphogenetic Protein 9 and Transforming Growth Factor Beta 1 Signaling. J Mol Biol. 2020 03 27; 432(7):2030-2041. Wang L, Yao J, Yu T, Zhang D, Qiao X, Yao Z, Wu X, Zhang L, Boström KI, Yao Y. PMID: 32061928; PMCID: PMC7225048.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    19. Skip is essential for Notch signaling to induce Sox2 in cerebral arteriovenous malformations. Cell Signal. 2020 04; 68:109537. Zhang D, Qiao X, Wang L, Zhang L, Yao J, Wu X, Yu T, Boström KI, Yao Y. PMID: 31927035; PMCID: PMC7147809.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    20. Elevated endothelial Sox2 causes lumen disruption and cerebral arteriovenous malformations. J Clin Invest. 2019 06 24; 129(8):3121-3133. Yao J, Wu X, Zhang D, Wang L, Zhang L, Reynolds EX, Hernandez C, Boström KI, Yao Y. PMID: 31232700; PMCID: PMC6668698.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    21. Crosstalk between BMP and Notch Induces Sox2 in Cerebral Endothelial Cells. Cells. 2019 06 06; 8(6). Wu X, Yao J, Wang L, Zhang D, Zhang L, Reynolds EX, Yu T, Boström KI, Yao Y. PMID: 31174355; PMCID: PMC6628192.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    22. Noggin depletion in adipocytes promotes obesity in mice. Mol Metab. 2019 07; 25:50-63. Blázquez-Medela AM, Jumabay M, Rajbhandari P, Sallam T, Guo Y, Yao J, Vergnes L, Reue K, Zhang L, Yao Y, Fogelman AM, Tontonoz P, Lusis AJ, Wu X, Boström KI. PMID: 31027994; PMCID: PMC6600080.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    23. SOX Transcription Factors in Endothelial Differentiation and Endothelial-Mesenchymal Transitions. Front Cardiovasc Med. 2019; 6:30. Yao Y, Yao J, Boström KI. PMID: 30984768; PMCID: PMC6447608.
      View in: PubMed   Mentions: 19  
    24. Endothelial Cells May Have Tissue-Specific Origins. J Cell Biol Histol. 2018 Jun; 1(1). Boström KI, Yao J, Wu X, Yao Y. PMID: 29974893; PMCID: PMC6028056.
      View in: PubMed   Mentions: 9  
    25. Vascular endothelium plays a key role in directing pulmonary epithelial cell differentiation. J Cell Biol. 2017 10 02; 216(10):3369-3385. Yao J, Guihard PJ, Wu X, Blazquez-Medela AM, Spencer MJ, Jumabay M, Tontonoz P, Fogelman AM, Boström KI, Yao Y. PMID: 28838957; PMCID: PMC5626536.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    26. Combined effects of bone morphogenetic protein 10 and crossveinless-2 on cardiomyocyte differentiation in mouse adipocyte-derived stem cells. J Cell Physiol. 2018 Mar; 233(3):1812-1822. Jumabay M, Zhumabai J, Mansurov N, Niklason KC, Guihard PJ, Cubberly MR, Fogelman AM, Iruela-Arispe L, Yao Y, Saparov A, Boström KI. PMID: 28464239; PMCID: PMC5668204.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    27. Endothelial-Mesenchymal Transition in Vascular Calcification of Ins2Akita/+ Mice. PLoS One. 2016; 11(12):e0167936. Guihard PJ, Yao J, Blazquez-Medela AM, Iruela-Arispe L, Boström KI, Yao Y. PMID: 27936229; PMCID: PMC5148029.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    28. Endothelial-mesenchymal transition in atherosclerotic lesion calcification. Atherosclerosis. 2016 10; 253:124-127. Boström KI, Yao J, Guihard PJ, Blazquez-Medela AM, Yao Y. PMID: 27615595; PMCID: PMC5064862.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    29. Matrix Gla protein regulates differentiation of endothelial cells derived from mouse embryonic stem cells. Angiogenesis. 2016 Jan; 19(1):1-7. Yao J, Guihard PJ, Blazquez-Medela AM, Guo Y, Liu T, Boström KI, Yao Y. PMID: 26364300; PMCID: PMC4703505.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    30. Serine Protease Activation Essential for Endothelial-Mesenchymal Transition in Vascular Calcification. Circ Res. 2015 Oct 09; 117(9):758-69. Yao J, Guihard PJ, Blazquez-Medela AM, Guo Y, Moon JH, Jumabay M, Boström KI, Yao Y. PMID: 26265629; PMCID: PMC4600461.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansAnimalsCells
    31. ABCC6 deficiency is associated with activation of BMP signaling in liver and kidney. FEBS Open Bio. 2015; 5:257-63. Blazquez-Medela AM, Guihard PJ, Yao J, Jumabay M, Lusis AJ, Boström KI, Yao Y. PMID: 25893161; PMCID: PMC4398664.
      View in: PubMed   Mentions: 4     Fields:    
    32. Matrix Gla protein limits pulmonary arteriovenous malformations in ALK1 deficiency. Eur Respir J. 2015 Mar; 45(3):849-52. Boström KI, Guihard P, Blazquez Medela AM, Yao J, Moon JH, Penton A, Yao Y. PMID: 25614167; PMCID: PMC4373345.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    33. Pluripotent stem cells derived from mouse and human white mature adipocytes. Stem Cells Transl Med. 2014 Feb; 3(2):161-71. Jumabay M, Abdmaulen R, Ly A, Cubberly MR, Shahmirian LJ, Heydarkhan-Hagvall S, Dumesic DA, Yao Y, Boström KI. PMID: 24396033; PMCID: PMC3925054.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    34. Reducing Jagged 1 and 2 levels prevents cerebral arteriovenous malformations in matrix Gla protein deficiency. Proc Natl Acad Sci U S A. 2013 Nov 19; 110(47):19071-6. Yao Y, Yao J, Radparvar M, Blazquez-Medela AM, Guihard PJ, Jumabay M, Boström KI. PMID: 24191040; PMCID: PMC3839731.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    35. A role for the endothelium in vascular calcification. Circ Res. 2013 Aug 16; 113(5):495-504. Yao Y, Jumabay M, Ly A, Radparvar M, Cubberly MR, Boström KI. PMID: 23852538; PMCID: PMC3851028.
      View in: PubMed   Mentions: 112     Fields:    Translation:HumansAnimalsCells
    36. Endothelial differentiation in multipotent cells derived from mouse and human white mature adipocytes. J Mol Cell Cardiol. 2012 Dec; 53(6):790-800. Jumabay M, Abdmaulen R, Urs S, Heydarkhan-Hagvall S, Chazenbalk GD, Jordan MC, Roos KP, Yao Y, Boström KI. PMID: 22999861; PMCID: PMC3523675.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    37. Crossveinless 2 regulates bone morphogenetic protein 9 in human and mouse vascular endothelium. Blood. 2012 May 24; 119(21):5037-47. Yao Y, Jumabay M, Ly A, Radparvar M, Wang AH, Abdmaulen R, Boström KI. PMID: 22474252; PMCID: PMC3367902.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    38. Patterns of periodic holes created by increased cell motility. Interface Focus. 2012 Aug 06; 2(4):457-64. Chen TH, Guo C, Zhao X, Yao Y, Boström KI, Wong MN, Tintut Y, Demer LL, Ho CM, Garfinkel A. PMID: 22649581; PMCID: PMC3363038.
      View in: PubMed   Mentions: 5  
    39. Concise review: applying stem cell biology to vascular structures. Stem Cells. 2012 Mar; 30(3):386-91. Boström KI, Garfinkel A, Yao Y, Jumabay M. PMID: 22232064; PMCID: PMC3592494.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    40. Abcc6 deficiency causes increased infarct size and apoptosis in a mouse cardiac ischemia-reperfusion model. Arterioscler Thromb Vasc Biol. 2011 Dec; 31(12):2806-12. Mungrue IN, Zhao P, Yao Y, Meng H, Rau C, Havel JV, Gorgels TG, Bergen AA, MacLellan WR, Drake TA, Boström KI, Lusis AJ. PMID: 21979437; PMCID: PMC3227394.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    41. Matrix Gla protein deficiency causes arteriovenous malformations in mice. J Clin Invest. 2011 Aug; 121(8):2993-3004. Yao Y, Jumabay M, Wang A, Boström KI. PMID: 21765215; PMCID: PMC3148746.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansAnimalsCells
    42. Activation of vascular bone morphogenetic protein signaling in diabetes mellitus. Circ Res. 2011 Feb 18; 108(4):446-57. Boström KI, Jumabay M, Matveyenko A, Nicholas SB, Yao Y. PMID: 21193740; PMCID: PMC3042480.
      View in: PubMed   Mentions: 100     Fields:    Translation:HumansAnimalsCells
    43. Inhibition of bone morphogenetic proteins protects against atherosclerosis and vascular calcification. Circ Res. 2010 Aug 20; 107(4):485-94. Yao Y, Bennett BJ, Wang X, Rosenfeld ME, Giachelli C, Lusis AJ, Boström KI. PMID: 20576934; PMCID: PMC2994650.
      View in: PubMed   Mentions: 120     Fields:    Translation:Animals
    44. Spontaneously beating cardiomyocytes derived from white mature adipocytes. Cardiovasc Res. 2010 Jan 01; 85(1):17-27. Jumabay M, Zhang R, Yao Y, Goldhaber JI, Boström KI. PMID: 19643806; PMCID: PMC2791054.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    45. Heat shock protein 70 enhances vascular bone morphogenetic protein-4 signaling by binding matrix Gla protein. Circ Res. 2009 Sep 11; 105(6):575-84. Yao Y, Watson AD, Ji S, Boström KI. PMID: 19661459; PMCID: PMC2779117.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    46. Expression of vascular endothelial growth factor is coordinately regulated by the activin-like kinase receptors 1 and 5 in endothelial cells. Blood. 2009 Sep 03; 114(10):2197-206. Shao ES, Lin L, Yao Y, Boström KI. PMID: 19506300; PMCID: PMC2744576.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansAnimalsCells
    47. High-density lipoproteins affect endothelial BMP-signaling by modulating expression of the activin-like kinase receptor 1 and 2. Arterioscler Thromb Vasc Biol. 2008 Dec; 28(12):2266-74. Yao Y, Shao ES, Jumabay M, Shahbazian A, Ji S, Boström KI. PMID: 18948634; PMCID: PMC2709402.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    48. Proline and gamma-carboxylated glutamate residues in matrix Gla protein are critical for binding of bone morphogenetic protein-4. Circ Res. 2008 May 09; 102(9):1065-74. Yao Y, Shahbazian A, Boström KI. PMID: 18369157.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    49. Matrix GLA protein, an inhibitory morphogen in pulmonary vascular development. J Biol Chem. 2007 Oct 12; 282(41):30131-42. Yao Y, Nowak S, Yochelis A, Garfinkel A, Boström KI. PMID: 17670744.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimals
    50. Activin-like kinase receptor 1 (ALK1) in atherosclerotic lesions and vascular mesenchymal cells. Cardiovasc Res. 2007 May 01; 74(2):279-89. Yao Y, Zebboudj AF, Torres A, Shao E, Boström K. PMID: 17074310.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    51. Regulation of bone morphogenetic protein-4 by matrix GLA protein in vascular endothelial cells involves activin-like kinase receptor 1. J Biol Chem. 2006 Nov 10; 281(45):33921-30. Yao Y, Zebboudj AF, Shao E, Perez M, Boström K. PMID: 16950789.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansAnimalsCells
    52. Matrix GLA protein stimulates VEGF expression through increased transforming growth factor-beta1 activity in endothelial cells. J Biol Chem. 2004 Dec 17; 279(51):52904-13. Boström K, Zebboudj AF, Yao Y, Lin TS, Torres A. PMID: 15456771.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimalsCells
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